Title:

Letter from Aaron Klug to Francis Crick

Creator:

Klug, Aaron

Recipient:

Crick, Francis, 1916-2004

Date:

12 October 1976

Description:

Klug here reports further results of X-ray diffraction studies of crystals of chromatin in his laboratory. Chromatin is a filamentary (stringy) assembly of DNA and associated basic proteins called histones. It is the form in which genes are organized on the chromosomes.. Nucleosomes, also mentioned in the letter, are distinct complexes of histone and DNA in eukaryotic cells (cells with clearly-defined nuclei), and form specific sections of chromatin. Under the electron microscope nucleosomes appear as bead-like bodies on a string of DNA.

Original Repository:

The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers

Location:

Box: 23. Folder: PP/CRI/D/2/18

Rights:

Reproduced with permission of Aaron Klug.

Genre:

Letters (correspondence)

Subject:

Crystallography, X-Ray, Chromatin, and Nucleosomes

Format:

Text

Extent:

2 pages

Relation:

Letter from Aaron Klug to Francis Crick, 1976

Language:

English

Legacy Source Citation:

Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/

Legacy ID:

SCBBPV

NLM ID:

101584582X222

Profiles Collection:

The Francis Crick Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584582X222

Story Section:

Embryology and the Organization of DNA in Higher Organisms, 1966-1976