Title:

Letter from Francis Crick to Charles A. Thomas

Creator:

Crick, Francis, 1916-2004

Recipient:

Thomas, Charles A., Jr

Date:

10 December 1979

Description:

Crick here elaborated on his idea that chromatin, the assembly of DNA and histones (proteins) that is found on the chromosomes of higher organisms, had a solenoid, or pipe-shaped, coiled form. In his letter he pointed out the limits of this idea, especially with regard to the irregular arrangement of the nucleosomes, distinct complexes of histone and DNA in the cells of higher organisms which are part of chromatin and which under the electron microscope appear as bead-like bodies on a string of DNA.

Original Repository:

The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers

Location:

Box: 23. Folder: PP/CRI/D/2/18

Rights:

Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/

Genre:

Letters (correspondence)

Subject:

Chromatin

Format:

Text

Extent:

1 pages

Language:

English

Legacy Source Citation:

Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/

Legacy ID:

SCBBPX

NLM ID:

101584582X224

Profiles Collection:

The Francis Crick Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584582X224

Story Section:

From Molecular Biology to Neurobiology, 1976-2004