Mutagenesis by Acridines in Bacteriophage T4


Title:
Mutagenesis by Acridines in Bacteriophage T4
Description:
In this lecture Crick provided an account of genetic experiments conducted with Leslie Barnett, Sydney Brenner, and Richard Watts-Tobin in 1961. In these experiments they used acridine mutants of viral DNA (mutants produced by chemicals of the acridine type, such as proflavin, which trigger additions to or deletions from the base sequence) in order to demonstrate that the genetic code was a three-letter code. They published their findings in a seminal article in Nature in December 1961, entitled "General Nature of the Genetic Code for Proteins."
Extent:
3 pages
Creator:
Crick, Francis, 1916-2004
Source:
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Right Type:
Permission Granted - No Conditions
Right Statement:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/
Subject:
Genetic Code
Profiles in Science ID:
SCBBCP
NLM ID:
101584582X23
Genre:
Lecture notes
Language:
English
Format:
Text
Location:
Box: 32. Folder: PP/CRI/E/1/9/12