Mutagenesis by Acridines in Bacteriophage T4
- Title:
- Mutagenesis by Acridines in Bacteriophage T4
- Creator:
- Crick, Francis, 1916-2004
- Date:
- [ca. 1961]
- Description:
- In this lecture Crick provided an account of genetic experiments conducted with Leslie Barnett, Sydney Brenner, and Richard Watts-Tobin in 1961. In these experiments they used acridine mutants of viral DNA (mutants produced by chemicals of the acridine type, such as proflavin, which trigger additions to or deletions from the base sequence) in order to demonstrate that the genetic code was a three-letter code. They published their findings in a seminal article in Nature in December 1961, entitled "General Nature of the Genetic Code for Proteins."
- Original Repository:
- The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
- Location:
- Box: 32. Folder: PP/CRI/E/1/9/12
- Rights:
- Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/
- Genre:
- Lecture notes
- Subject:
- Genetic Code
- Format:
- Text
- Extent:
- 3 pages
- Relation:
- General Nature of the Genetic Code for Proteins, 1961
- Language:
- English
- Legacy Source Citation:
- Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
- Legacy ID:
- SCBBCP
- NLM ID:
- 101584582X23
- Profiles Collection:
- The Francis Crick Papers
- Shareable Link:
- https://profiles.nlm.nih.gov/101584582X23
- Story Section:
- Deciphering the Genetic Code, 1958-1966