Letter from Francis Crick to Aaron Klug


Title:
Letter from Francis Crick to Aaron Klug
Description:
Crick here commented again on the draft of a paper by Klug on the spatial arrangement of DNA and histones (proteins associated with DNA) in nucleosomes, particularly on the dimensions of the DNA helix, whether the DNA helix was itself coiled in a nucleosome (forming a coiled coil, or superhelix), and the number of base pairs per turn of the superhelix. Crick also pointed out that as DNA shrank from its hydrated, elongated B form (or fiber form) to its shorter, drier A form, the X-ray diffraction patterns of DNA in nucleosomes changed in ways that might affect Klug's conclusions.
Extent:
2 pages
Date Created:
30 June 1977
Creator:
Crick, Francis, 1916-2004
Recipient:
Klug, Aaron (Aaron Klug)
Source:
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Right Type:
Permission Granted - No Conditions
Right Statement:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/
Subject:
DNA, Nucleosomes, and Crystallography, X-Ray
Profiles in Science ID:
SCBBQG
NLM ID:
101584582X231
Genre:
Letters (correspondence)
Language:
English
Format:
Text
Location:
Box: 23. Folder: PP/CRI/D/2/18