Letter from Francis Crick to Aaron Klug
- Title:
- Letter from Francis Crick to Aaron Klug
- Creator:
- Crick, Francis, 1916-2004
- Recipient:
- Klug, Aaron
- Date:
- 20 June 1977
- Description:
- Crick here commented further on the draft of a paper by Klug on the spatial arrangement of DNA and histones (proteins associated with DNA) in nucleosomes. Particularly, Crick debated the dimensions of the DNA helix in nucleosomes and how the DNA helix was itself coiled in a nucleosome (forming a coiled coil, or superhelix). Nucleosomes have since been determined to consist of eight histone molecules wrapped by a DNA segment of about 150 base pairs in length. Under the electron microscope nucleosomes, which are linked to each other by DNA sequences about fifty base pairs in length, appear as bead-like bodies on a string.
- Original Repository:
- The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
- Location:
- Box: 23. Folder: PP/CRI/D/2/18
- Rights:
- Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/
- Genre:
- Letters (correspondence)
- Subject:
- DNA and Nucleosomes
- Format:
- Text
- Extent:
- 2 pages
- Relation:
- Letter from Aaron Klug to Francis Crick, 1977 Letter from Francis Crick to Aaron Klug, 1977 Letter from Francis Crick to Aaron Klug, 1977
- Language:
- English
- Legacy Source Citation:
- Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
- Legacy ID:
- SCBBQH
- NLM ID:
- 101584582X232
- Profiles Collection:
- The Francis Crick Papers
- Shareable Link:
- https://profiles.nlm.nih.gov/101584582X232
- Story Section:
- From Molecular Biology to Neurobiology, 1976-2004