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In his letter Crick drew on his broad knowledge of X-ray crystallography in commenting on Klug's recent hypotheses regarding the three-dimensional configuration of atoms within nucleosomes, compounds of chromosomal DNA and histones (proteins that have a structural or scaffolding function) that appear like beads on a string under the electron microscope.
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Location:
Box: 23. Folder: PP/CRI/D/2/18
Rights:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/