Title:

Letter from Francis Crick to Robert L. Sinsheimer

Creator:

Crick, Francis, 1916-2004

Recipient:

Sinsheimer, Robert

Date:

9 October 1961

Description:

In this letter Crick refers to genetic experiments undertaken with Leslie Barnett, Sydney Brenner, and Richard Watts-Tobin on acridine mutants, which indicated that the genetic code was a triplet code. Compelling evidence that poly-U (a synthetic form of RNA consisting of bases of a single type, uracil) coded for the amino acid phenylalanine was first presented by the American biochemist Marshall Nirenberg in the summer of 1961.

Original Repository:

The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers

Location:

Box: 32. Folder: PP/CRI/E/1/10/4/3

Rights:

Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/

Genre:

Letters (correspondence)

Subject:

Genetic Code

Format:

Text

Extent:

1 pages

Language:

English

Legacy Source Citation:

Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/

Legacy ID:

SCBBCQ

NLM ID:

101584582X24

Profiles Collection:

The Francis Crick Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584582X24

Story Section:

Deciphering the Genetic Code, 1958-1966