Letter from Francis Crick to Aaron Klug


Title:
Letter from Francis Crick to Aaron Klug
Description:
Crick expressed reservations about the evidence used by his two co-authors in support of their idea that chromatids, the one-half of a chromosome that splits off from the other half during cell division, were organized in a hierarchy of helices: the chromatid is a folded and coiled super-solenoid (a long, regular, hollow cylindrical structure), also called the unit fiber, which in turn is formed by a coiled solenoid of smaller diameter, which in turn is formed by coiling the string of nucleosomes, bead-like complexes of DNA and protein.. See Leth Bak, Jesper Zeuthen, and Crick, "Higher-Order Structure of Human Mitotic Chromosomes," Proceedings of the National Academy of Sciences, vol. 74 (April 1977), pp. 1595-99.
Extent:
2 pages
Date Created:
17 January 1977
Creator:
Crick, Francis, 1916-2004
Recipient:
Klug, Aaron (Aaron Klug)
Source:
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Right Type:
Permission Granted - No Conditions
Right Statement:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/
Subject:
DNA and Chromatids
Profiles in Science ID:
SCBBQT
NLM ID:
101584582X242
Genre:
Letters (correspondence)
Language:
English
Format:
Text
Location:
Box: 23. Folder: PP/CRI/D/2/18