Letter from Francis Crick to Aaron Klug
- Title:
- Letter from Francis Crick to Aaron Klug
- Creator:
- Crick, Francis, 1916-2004
- Recipient:
- Klug, Aaron
- Date:
- 17 January 1977
- Description:
- Crick expressed reservations about the evidence used by his two co-authors in support of their idea that chromatids, the one-half of a chromosome that splits off from the other half during cell division, were organized in a hierarchy of helices: the chromatid is a folded and coiled super-solenoid (a long, regular, hollow cylindrical structure), also called the unit fiber, which in turn is formed by a coiled solenoid of smaller diameter, which in turn is formed by coiling the string of nucleosomes, bead-like complexes of DNA and protein.. See Leth Bak, Jesper Zeuthen, and Crick, "Higher-Order Structure of Human Mitotic Chromosomes," Proceedings of the National Academy of Sciences, vol. 74 (April 1977), pp. 1595-99.
- Original Repository:
- The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
- Location:
- Box: 23. Folder: PP/CRI/D/2/18
- Rights:
- Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/
- Genre:
- Letters (correspondence)
- Subject:
- DNA and Chromatids
- Format:
- Text
- Extent:
- 2 pages
- Relation:
- Letter from Aaron Klug to Francis Crick, 1977 Letter from Aaron Klug to Francis Crick, 1977 Higher-Order Structure of Human Mitotic Chromosomes, 1977
- Language:
- English
- Legacy Source Citation:
- Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/
- Legacy ID:
- SCBBQT
- NLM ID:
- 101584582X242
- Profiles Collection:
- The Francis Crick Papers
- Shareable Link:
- https://profiles.nlm.nih.gov/101584582X242
- Story Section:
- From Molecular Biology to Neurobiology, 1976-2004