Metin and Metactomyosin


Title:
Metin and Metactomyosin
Creator:
Kaminer, B.
Szent-Gyorgyi, Albert, 1893-1986
Date:
15 December 1963
Description:
This study sought to explain the apparent role of calcium ions in muscle contraction, by searching for a component of muscle tissue that would have an affinity for Ca ions. Reasoning that such material would probably have a structure that included negative groups such as sulfites, and knowing that such molecules were often "metachromatic" (i.e., would stain to a different color than that of the dye applied to them), Szent-Gyorgyi tested various muscle components--myosin, actomyosin, and other fractions--for their ability to turn toluidine blue (a lab stain) purple. He extracted a metachromatic protein and called it "metin."
Periodical:
Proceedings of the National Academy of Sciences of the United States of America
Publisher:
National Academy of Sciences (U.S.)
Rights:
Reprinted with permission from the National Foundation for Cancer Research. For additional copies or more information, please call 1-800-321-CURE or visit our Web site at and http://www.nfcr.org/
Genre:
Articles
Subject:
Muscle Contraction and Calcium
Format:
Text
Extent:
4 pages
Language:
English
Legacy Source Citation:
Periodical. Szent-Gyorgyi, Albert, and B. Kaminer. "Metin and Metactomyosin." Proceedings of the National Academy of Sciences of the United States of America 50, 6 (15 December 1963): 1033-1036. Article. 4 Images.. Proceedings of the National Academy of Sciences of the United States of America
Legacy ID:
WGBBHZ
NLM ID:
101584924X124
Profiles Collection:
The Albert Szent-Gyorgyi Papers
Story Section:
The Institute for Muscle Research, 1947-1972