Official websites use .gov A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
In the early 1950s, the extremely effective antihypertensive drug reserpine, a pure active alkaloid of the tropical plant rauwolfia, became available for clinical use. In this article, Freis reported that in high doses reserpine resulted in severe mental depression.
Hypertension, Antihypertensive Agents, Reserpine, and Depression
Format:
Text
Extent:
2 pages
Language:
English
Legacy Source Citation:
Periodical. Freis, Edward D. "Mental Depression in Hypertensive Patients Treated for Long Periods with Large Doses of Reserpine." New England Journal of Medicine 251, (16 December 1954): 1006-1008. Article. 2 Images.. New England Journal of Medicine