Title:

Clinical Trial of Guanethidine, a New Type of Antihypertensive Agent

Creator:

Frohlich, Edward D.
Freis, Edward D.

Date:

August 1959

Description:

Throughout the 1950s and 1960s several ganglionic-blocking agents were introduced that provided a variety of options for clinicians treating high blood pressure. These agents reduced blood pressure by interfering with nerve impulses from the brain that constricted blood vessels. In this article, Freis and Frohlich reported that one of these agents, guanethidine, exhibited a potent, orthostatic, antihypertensive effect similar to other ganglionic-blocking agents.

Periodical:

The Medical Annals of the District of Columbia

Publisher:

Medical Society of the District of Columbia

Location:

Box: 7. Folder: 11

Rights:

Public Domain

Genre:

Articles

Subject:

Hypertension, Antihypertensive Agents, and Guanethidine

Format:

Text

Extent:

4 pages

Language:

English

Legacy Source Citation:

Periodical. Frohlich, Edward D., and Edward D. Freis. "Clinical Trial of Guanethidine, a New Type of Antihypertensive Agent." The Medical Annals of the District of Columbia XXVIII, 8 (August 1959): 419-422. Article. 4 Images.. The Medical Annals of the District of Columbia

Legacy ID:

XFBBDJ

NLM ID:

101584929X49

Profiles Collection:

The Edward D. Freis Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584929X49

Story Section:

The Veterans Administration Hospital and Georgetown University School of Medicine, 1949-1964