Official websites use .gov
Secure .gov websites use HTTPS
Double Blind Control Study of Antihypertensive Agents: III. Chlorothiazide Alone and in Combination with Other Agents; Preliminary Results
- Title:
- Double Blind Control Study of Antihypertensive Agents: III. Chlorothiazide Alone and in Combination with Other Agents; Preliminary Results
- Creator:
- Veterans Administration Cooperative Study Group on Antihypertensive Agents
- Date:
- August 1962
- Description:
- In 1956, Freis and a group of physicians in several Veterans Administration hospitals organized a cooperative study group to evaluate antihypertensive agents under well-controlled conditions. In this third and final article, they reported that treatment of hypertensive patients with the diuretic chlorothiazide compared favorably to earlier studies in which patients were treated with a combination of reserpine (a ganglionic-blocking agent) and hydralazine (a vasodilator). They further noted that patients from the earlier study who were then treated with chlorothiazide recorded even greater reductions in their blood pressure, even if the dosages of ganglionic blockers were reduced.
- Periodical:
- Archives of Internal Medicine
- Publisher:
- American Medical Association
- Location:
- Box: 7. Folder: 14
- Rights:
- Public Domain
- Genre:
- Articles
- Subject:
- Hypertension, Antihypertensive Agents, Chlorothiazide, Reserpine, and Hydralazine
- Format:
- Text
- Extent:
- 7 pages
- Relation:
- A Double Blind Control Study of Antihypertensive Agents: I. Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglionic Blocking Agents, Chlorisondamine, Mecamyamine, and Pentolinium Tartrate, 1960 Double Blind Control Study of Antihypertensive Agents: II. Further Report on the Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglion Blocking Agents, Chlorisondamine, Mecamylamine, and Pentolinium Tartrate, 1962
- Language:
- English
- Legacy Source Citation:
- Periodical. Veterans Administration Cooperative Study Group on Antihypertensive Agents. "Double Blind Control Study of Antihypertensive Agents: III. Chlorothiazide Alone and in Combination with Other Agents; Preliminary Results." Archives of Internal Medicine 110, (August 1962): 230-236. Article. 7 Images.. Archives of Internal Medicine
- Legacy ID:
- XFBBFB
- NLM ID:
- 101584929X63
- Profiles Collection:
- The Edward D. Freis Papers
- Shareable Link:
- https://profiles.nlm.nih.gov/101584929X63
- Story Section:
- The Veterans Administration Hospital and Georgetown University School of Medicine, 1949-1964