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In this essay, Freis discussed the physiological impact on the heart and arteries due to hypertension. He also discussed the effect of diuretics, which reduce plasma volume.
Periodical. Freis, Edward D. "Hemodynamic Changes in Hypertension." The Medical Clinics of North America 45, 2 (March 1961): 239-245. Article. 7 Images.. The Medical Clinics of North America