Title:

Enzymatic O-Methylation of N-Acetylserotonin to Melatonin

Creator:

Axelrod, Julius, 1912-2004
Weissbach, Herbert.

Date:

29 April 1960

Description:

In this brief article, Axelrod and Weissbach reported their isolation of an enzyme, hydroxyindole-O-methyl transferase (HIOMT), which plays a key role in the formation of melatonin by the methylation of serotonin.

Periodical:

Science

Publisher:

American Association for the Advancement of Science

Location:

Box: 22. Folder: 14

Rights:

Reproduced with permission from the American Association for the Advancement of Science. Readers may view, browse, and/or download this material for temporary copying purposes only, provided these uses are for noncommercial personal purposes. Except as provided by law, this material may not be further reproduced, distributed, transmitted, modified, adapted, performed, displayed, published, or sold in whole or in part, without prior written permission from AAAS. and http://www.sciencemag.org/

Genre:

Articles

Subject:

Pineal Gland, Melatonin, and Acetylserotonin O-Methyltransferase

Format:

Text

Extent:

1 pages

Language:

English

Legacy Source Citation:

Periodical. Axelrod, Julius, and Herbert Weissbach. "Enzymatic O-Methylation of N-Acetylserotonin to Melatonin." Science 131, (29 April 1960): 1312. Article. 1 Image.. Science

Legacy ID:

HHAABU

NLM ID:

101584577X47

Profiles Collection:

The Julius Axelrod Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584577X47

Story Section:

The Pineal Gland and the "Melatonin Hypothesis," 1959-1974