Official websites use .gov A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
As Crick noted in this letter, the details of the structure of DNA were not yet conclusively established in 1977, beyond the base pairing and the antiparallel arrangement of the sugar-phosphate backbones, more than two decades after Watson and Crick proposed that it was a double helix. In the absence of definitive experimental proof, some researchers continued to suggest alternative structures. In this instance, Crick responded to an argument by Rodley that the two chains of DNA were straight rather than helical. He found such a structure unlikely, but nonetheless suggested how experimental proof for it might be produced, if at all.
Original Repository:
The Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers
Location:
Box: 23. Folder: PP/CRI/D/2/18
Rights:
Reproduced with permission of the Wellcome Library for the History and Understanding of Medicine. and http://library.wellcome.ac.uk/
Original Repository. Wellcome Library for the History and Understanding of Medicine. Francis Harry Compton Crick Papers. 11646. URL. http://archives.wellcome.ac.uk/