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NOTE: The page numbers in this notebook are not sequential. Gaps in the pagination from pages 23 to 467 reflect the fact that were originally pulled by Dr. Lederberg from his laboratory notebooks, "Wisconsin [I]" and "Wisconsin [II]". In turn, the gaps in the latter notebooks are reflected here. Starting with page 500, gaps in the pagination are of a different set of experiments and will be found in Lederberg laboratory notebook, "Salmonella."