Title:

ATP? or GTP

Creator:

Rodbell, Martin, 1925-1998

Date:

[ca. January 1970]

Description:

This fourth chart compares the differences between ATP and GTP in dissociating pre-bound glucagon from a liver membrane cell receptor. As one can see by the charted lines in the upper right hand corner of the page, a smaller concentration of GTP could dissociate what a much larger concentration of ATP could accomplish in the same period of time. From these experiments, Rodbell concluded that, of all the nucleotides, GTP was the most effective biological catalyst.

Location:

Box: 16. Folder: 9

Rights:

Courtesy of Fernando Ribeiro-Neto.

Disclaimer:

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Genre:

Laboratory notes
Graphs

Subject:

Adenosine Triphosphate and Guanosine Triphosphate

Format:

Text

Extent:

1 pages

Relation:

Influence of Additions on Glucagon Binding, 1969
Effect of Nucleotides, 1970
Release of Glucagon -- I-125, 1970

Language:

English

Legacy ID:

GGAAAV

NLM ID:

101584917X22

Profiles Collection:

The Martin Rodbell Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584917X22

Story Section:

Signal Transduction and the Discovery of G-Proteins, 1969-1980