Title:

Possible Model for Viral Gene Expression in Nonpermissive Cells

Creator:

UCSF

Date:

[1978]

Description:

This schematic drawing pictures how the genes of a transforming (cancer-causing) virus may be read, or expressed, by the infected cell's genetic machinery. The machinery includes messenger RNA (mRNA) and protein-producing structures called ribosomes. The cell type here is non-permissive, meaning a type or species of cell in which a particular virus cannot complete its replication cycle. The transforming protein--one that stimulates expression of genes controlling cell division, leading to cancerous growth--is produced, but no copies of the virus itself are made or released from the cell.

Original Repository:

University of California, San Francisco. Archives and Special Collections. Harold E. Varmus Papers

Location:

Box: 7. Folder: 5

Rights:

Reproduced with permission of the Regents of the University of California.

Genre:

Slides (photographs)
Charts (graphic documents)

Subject:

Avian Sarcoma Viruses

Format:

Still Image

Extent:

1 pages

Language:

English

Legacy Source Citation:

Original Repository. University of California, San Francisco. Archives and Special Collections. Harold E. Varmus Papers. 12290

Legacy ID:

MVBBJF

NLM ID:

101584926X124

Profiles Collection:

The Harold Varmus Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584926X124

Story Section:

Retroviruses and the Genetic Origins of Cancer, 1970-1993