Title:

Critique of the Clinical Importance of Diurectic-Induced Hypokalemia and Elevated Cholesterol Level

Creator:

Freis, Edward D.

Date:

December 1989

Description:

In this commentary, Freis argued that one of the more disappointing outcomes of the antihypertensive drug trials has been the failure to curb the morbidity rate due to coronary heart disease (CHD). He noted that some have hypothesized that the continued high death rate from CHD was due in part to thiazide-induced hypokalemia. After reviewing various studies on both sides of the debate, Freis concluded that the evidence did not support the argument that diuretic use contributed to CHD.. NOTE: "Diuretic" is misspelled in the original article's title line.

Periodical:

Archives of Internal Medicine

Publisher:

American Medical Association

Location:

Box: 7. Folder: 13

Rights:

Public Domain

Genre:

Articles

Subject:

Hypertension, Antihypertensive Agents, Hypokalemia, Diuretics, Thiazides, and Cholesterol

Format:

Text

Extent:

9 pages

Relation:

Thiazide Therapy Is Not a Cause of Arrhythmia in Patients with Systemic Hypertension, 1988

Language:

English

Legacy Source Citation:

Periodical. Freis, Edward D. "Critique of the Clinical Importance of Diurectic-Induced Hypokalemia and Elevated Cholesterol Level." Archives of Internal Medicine 149, (December 1989): 2640-2648. Article. 9 Images.. Archives of Internal Medicine

Legacy ID:

XFBBDR

NLM ID:

101584929X55

Profiles Collection:

The Edward D. Freis Papers

Shareable Link:

https://profiles.nlm.nih.gov/101584929X55

Story Section:

After 1980: Changing Trends in Hypertension Therapy