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Double Blind Control Study of Antihypertensive Agents: II. Further Report on the Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglion Blocking Agents, Chlorisondamine, Mecamylamine, and Pentolinium Tartrate
Double Blind Control Study of Antihypertensive Agents: II. Further Report on the Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglion Blocking Agents, Chlorisondamine, Mecamylamine, and Pentolinium Tartrate
In 1956, Freis and a group of physicians in several Veterans Administration hospitals organized a cooperative study group to evaluate antihypertensive agents under well-controlled conditions. In this second of three articles, they confirmed some of the general findings of the first report, that a regimen of reserpine (a ganglionic-blocking agent) combined with hydralazine (a vasodilator) produced far better results than the use of ganglionic-blocking agents alone.
Periodical. Veterans Administration Cooperative Study Group on Antihypertensive Agents. "Double Blind Control Study of Antihypertensive Agents: II. Further Report on the Comparative Effectiveness of Reserpine, Reserpine and Hydralazine, and Three Ganglion Blocking Agents, Chlorisondamine, Mecamylamine, and Pentolinium Tartrate." Archives of Internal Medicine 110, (August 1962): 222-229. Article. 8 Images.. Archives of Internal Medicine