I must thank you again for your kindness and thoughtfulness in sending me the photograph of Fred Griffith and the Xerox copy
of your letter to Fess Avery. Some time I wonder if you would be interested to write the intellectual history of the interaction
of these men. I have always been fascinated on exactly what Griffith thought of his experiment and just how deeply Avery
understood the genetic implications in a broader context of what he took up from that. The significance of all these observations
was, as you know, somewhat clouded by a semantic confusion about directed mutation in contrast to gene transfer. Griffith
seemed quite clear about this. I have never been able to straighten out in my own mind whether Avery bothered very much about
these genetic issues. I have written a little about this in the enclosed remarks, and would be interested to know if you
had any comment on the writing.