Title:

The Elaboration of Specific Soluble Substance by Pneumococcus During Growth

Creator:

Avery, Oswald Theodore, 1877-1955
Dochez, A. R. (Alphonse Raymond)

Date:

[2-3 May 1917]

Description:

Dochez and Avery discovered that culture fluids of pneumococci which were filtered to remove bacteria contained a substance in solution that precipitated when added to certain antisera, and which proved to be type specific. They reasoned that this component, which they called the "specific soluble substance," or SSS, was released in the body from the masses of pneumococci in the lungs of pneumonia patients and then excreted from the kidney and therefore present in patients' urine. Thus, it was possible to diagnose the type of pneumonia with which a person was infected by means of a simple urine test.

Periodical:

Transactions of the Association of American Physicians

Publisher:

Blackwell Scientific Publications

Rights:

Public Domain

Genre:

Articles

Format:

Text

Extent:

18 pages

Relation:

The Soluble Specific Substance of Pneumococcus, 1923
Immunologic Relationships of Cell Constituents of Pneumococcus, 1923
The Soluble Specific Substance of Pneumococcus: Second Paper, 1924

Language:

English

Legacy Source Citation:

Periodical. Dochez, A. R., and Oswald T. Avery. "The Elaboration of Specific Soluble Substance by Pneumococcus During Growth." Transactions of the Association of American Physicians 32, ([2-3 May 1917]): 281-298. Article. 18 Images.. Transactions of the Association of American Physicians

Legacy ID:

CCGMBK

NLM ID:

101584575X530

Profiles Collection:

The Oswald T. Avery Collection

Shareable Link:

https://profiles.nlm.nih.gov/101584575X530

Story Section:

The "Sugar-Coated Microbe" and the Search for a Cure for Pneumonia, 1919-1929